February 2025 Archive — Practical Pharmacy Guides
This month we published two practical pieces that patients and caregivers will find useful. One looks at how central cranial diabetes insipidus affects dental health and gives clear hygiene tips. The other breaks down real alternatives to Inderal, focusing on Rimegepant for migraine prevention. Read on for the key takeaways and quick actions you can use today.
Dental health with central cranial diabetes insipidus
If you or someone you care for has central cranial diabetes insipidus, dry mouth and frequent thirst can make cavities and gum problems more likely. Start with hydration: sip water regularly instead of gulping large amounts at once, which can help maintain saliva flow without upsetting sleep. Use a fluoride toothpaste twice daily and a soft-bristled brush to protect enamel that’s more exposed when saliva is low. Consider a daily alcohol-free mouthwash with fluoride and look for saliva substitutes or oral moisturizing gels at night to reduce overnight dryness.
Schedule dental checkups more often than usual — every three to four months if possible — so your dentist can catch early signs of decay or gum disease. Bring a list of medications and any changes in hydration when you visit; some drugs and fluid shifts affect oral tissues. If you experience sudden changes like persistent bad breath, bleeding gums, or new tooth sensitivity, see your dentist sooner rather than later.
Simple habits help a lot: avoid sticky sweets, choose sugar-free gum to stimulate saliva when awake, and use a humidifier while sleeping to reduce mouth dryness. If you use desmopressin or other treatments for DI, discuss with your prescriber how dosing affects hydration and oral health so both your endocrine and dental care teams stay coordinated.
Alternatives to Inderal: what to consider about Rimegepant
Not everyone can tolerate beta-blockers like Inderal for migraine prevention. Rimegepant, a CGRP receptor antagonist, shows promise as an alternative for many people. It often has fewer cardiovascular effects than beta-blockers, which matters if you have high blood pressure, asthma, or other heart concerns. Think about cost and access: newer migraine drugs can be pricier and may need prior authorization from insurance.
Effectiveness varies by person. Rimegepant can reduce migraine days for many users, but talk to your neurologist about your headache pattern, other meds, and any liver or kidney issues. Ask about side effects like nausea or fatigue and whether a trial period is appropriate. If you’re pregnant, breastfeeding, or planning pregnancy, discuss safety with your doctor — newer agents may lack long-term pregnancy data.
Before changing therapy, list your goals: fewer migraine days, fewer rescue meds, or better tolerability. Track headaches and side effects for 8–12 weeks to judge if a new drug helps. If cost is a barrier, ask your prescriber about samples, manufacturer savings, or step therapy options through your insurer.
Both posts aim to give clear, usable steps you can try now. Visit the full articles on plushcare.com for deeper details and sources, and bring your notes to your next provider visit to make decisions faster and safer.
, Feb, 23 2025
People with central cranial diabetes insipidus often face unique challenges when it comes to dental health. The lack of saliva due to frequent urination and dehydration can lead to more cavities and gum problems. This article offers practical tips for maintaining oral hygiene, focuses on the importance of hydration, and suggests products that can help manage these dental challenges effectively.
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